IpiRecord: IPI00324758

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
integral to plasma membrane	C		IEA	ISS
T-tubule	C			IDA
nuclear membrane	C			IDA
integral to membrane	C		IEA IEA	IEA
membrane	C		IEA	IDA ISS IEA
protein binding	F		IPI IPI	ISS IEA
receptor activity	F		IEA	IEA
protein-tyrosine kinase activity	F		TAS
rhodopsin-like receptor activity	F		IEA	IEA
endothelin receptor activity	F		IMP	TAS ISS IEA
signal transducer activity	F		IEA
G-protein coupled receptor activity	F		TAS IEA	ISS
endothelin-A receptor activity	F			IDA ISS
phosphoinositide phospholipase C activity	F			ISS
respiratory gaseous exchange	P		IMP IMP	ISS IEA
response to hypoxia	P		IMP	ISS IEA
positive regulation of inflammatory response	P			IMP
negative regulation of cAMP biosynthetic process	P		IGI	ISS IEA
phospholipase C activation	P			ISS
regulation of epithelial cell proliferation	P			IMP
G-protein coupled receptor protein signaling pathway	P		TAS IEA	ISS ISS IEA
positive regulation of calcium ion transport	P			IMP
elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)	P			IMP
neural crest cell development	P		IMP IMP	ISS IEA
cell proliferation	P			ISS
smooth muscle contraction	P			ISS
in utero embryonic development	P		IMP	ISS IEA
response to morphine	P			IMP
vasoconstriction	P		IMP	IMP ISS IEA
blood pressure regulation	P		IMP
positive regulation of protein amino acid phosphorylation	P			IMP
protein kinase C activation	P			IMP
adenylate cyclase activation	P			ISS
heart development	P		IGI	ISS IEA
glucose transport	P		IDA	ISS IEA
positive regulation of release of sequestered calcium ion into cytosol	P			IMP
elevation of cytosolic calcium ion concentration	P			IDA ISS
signal transduction	P		IEA	ISS IEA
patterning of blood vessels	P		IGI	ISS IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (23)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
craniofacial phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
hearing/vestibular/ear phenotype	MP		Un
immune system phenotype	MP		Un
embryogenesis phenotype	MP		Un
lethality-embryonic/perinatal	MP		Un
hematopoietic system phenotype	MP		Un
skeleton phenotype	MP		Un
muscle phenotype	MP		Un
renal/urinary system phenotype	MP		Un
digestive/alimentary phenotype	MP		Un
cardiovascular system phenotype	MP		Un Un
nervous system phenotype	MP		Un
respiratory system phenotype	MP		Un
normal phenotype	MP		Un
increased systolic blood pressure	N			IED
proteinuria	N			IED
glomerulosclerosis	N			IED
acute pancreas inflammation	N			IED
kidney cysts	N			IMP
left ventricle hypertrophy	N			IED
renal interstitial fibrosis	N			IMP

Disease (5)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Hypertension, Pulmonary	D			IED
Myocardial Infarction	D			IED
Myocardial Ischemia	D			ISS
Migraine	D			ISS
Hypertension	D			IEDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Neuroactive ligand-receptor interaction (04080)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Calcium signaling pathway (04020)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway