IpiRecord: IPI00324943

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
plasma membrane	C	TAS TAS		ISS
cell surface	C			IDA
membrane	C			IEA
external side of plasma membrane	C		IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA IDA	ISS
integral to membrane	C	IEA		IEA
interleukin-2 binding	F		IPI	ISS
interleukin-2 receptor activity	F	TAS	IMP	ISS ISS IPI
receptor activity	F	IEA	IEA	IEA
negative regulation of T cell proliferation	P		IMP	ISS
inflammatory response to antigenic stimulus	P			IMP
T cell homeostasis	P		IMP	ISS
regulation of progression through cell cycle	P	NR		ISS
negative regulation of inflammatory response	P		IMP IMP	ISS
cell surface receptor linked signal transduction	P	TAS		ISS
positive regulation of activated T cell proliferation	P		IMP	ISS
cell proliferation	P	TAS		ISS
apoptosis	P	TAS		ISS
positive regulation of apoptosis	P		IMP	ISS
positive regulation of T cell differentiation	P			IMP
immune response	P	TAS		ISS
activated T cell apoptosis	P		IMP	ISS
negative regulation of lymphocyte proliferation	P		IMP
positive regulation of T cell proliferation	P			IMP
regulation of T cell homeostatic proliferation	P		IMP

Cellular Component

Biological Process

Molecular Function

Phenotype (5)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
immune system phenotype	MP		Un
digestive/alimentary phenotype	MP		Un
hematopoietic system phenotype	MP		Un
growth/size phenotype	MP		Un
life span-post-weaning/aging	MP		Un

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Lymphopenia	D			ISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Hematopoietic cell lineage (04640)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cytokine-cytokine receptor interaction (04060)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway