IpiRecord: IPI00324966

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
plasma membrane	C			ISS
membrane	C		IEA	IEA
membrane fraction	C		IDA	ISS IEA
cellular_component	C			ND
integral to plasma membrane	C			ISS
integral to membrane	C		IEA IEA	IEA
receptor activity	F		IEA	IEA
adrenoceptor activity	F		RCA	ISS IEA
G-protein coupled receptor activity	F		IEA
alpha1-adrenergic receptor activity	F		ISS IMP IDA	IDA ISS ISS IEA
rhodopsin-like receptor activity	F		IEA	IEA
signal transducer activity	F		IEA
negative regulation of cell proliferation	P			ISS
adult heart development	P		IGI	ISS IEA
G-protein coupled receptor protein signaling pathway	P		IEA IEA	ISS
positive regulation of action potential	P			IMP
positive regulation of MAPKKK cascade	P		IGI	ISS IEA
cell-cell signaling	P			ISS
smooth muscle contraction	P			ISS
positive regulation of heart contraction rate by epinephrine-norepinephrine	P		IGI	ISS IEA
increased strength of heart contraction by epinephrine-norepinephrine	P		IGI	ISS IEA
positive regulation of vasoconstriction	P			IDA
phospholipase C activation	P			IDA
protein kinase cascade	P			ISS
response to stress	P			IDA
blood pressure regulation	P			ISS
negative regulation of synaptic transmission, GABAergic	P			IDA
signal transduction	P		IEA	ISS IEA
negative regulation of heart contraction rate in baroreceptor response to increased blood pressure	P		IMP	ISS IEA
G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)	P		IDA	ISS
cell growth	P		IGI	ISS IEA
elevation of cytosolic calcium ion concentration	P			ISS IMP
organ growth	P		IGI	ISS IEA
norepinephrine-epinephrine vasoconstriction during regulation of blood pressure	P		IMP	ISS IEA
response to drug	P			IMP
response to hormone stimulus	P			IMP
aging	P			IDA
apoptosis	P			ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (5)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
homeostasis/metabolism phenotype	MP		Un
muscle phenotype	MP		Un
renal/urinary system phenotype	MP		Un
cardiovascular system phenotype	MP		Un
life span-post-weaning/aging	MP		Un

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Diabetes Mellitus, Experimental	D			IEP
Hypotension	D			IED
Hypertension	D			IEP

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
G protein signaling pathway via Galphaq family	W			ISS

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Neuroactive ligand-receptor interaction (04080)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Calcium signaling pathway (04020)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway