| IPI00325506 - Abcg5, ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 5. | |
|---|---|
| Uniprot Accession: Q923R8 | |
| Uniprot ID: Q923R8_RAT | |
| Mapping: Chr 6, 8027647 - 8064425 | |
| Entrez Gene: 114628 | |
| Entrez MapView: |
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| RGD: 620298 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6106) |
|---|
| Rat: Abcg5, ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 5. |
| Mouse: Abcg5, ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 5. |
| Human: ABCG5, ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 5. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular_component | C | ND | ||
| membrane | C | IEA | IEA | IEA |
| ATP-binding cassette (ABC) transporter complex | C | TAS | ||
| integral to membrane | C | IEA | RCA | IEA ISS |
| nucleoside-triphosphatase activity | F | IEA | ||
| ATP binding | F | IEA | IEA IEA | IEA |
| cholesterol transporter activity | F | TAS | ||
| ATPase activity | F | IEA | IEA | IEA |
| molecular_function | F | ND | ||
| nucleotide binding | F | IEA | IEA IEA | IEA |
| sterol transport | P | TAS | ||
| response to nutrient | P | IEP | ||
| cholesterol transport | P | TAS | ||
| regulation of cholesterol absorption | P | TAS ISS | ||
| response to ionizing radiation | P | IEP | ||
| transport | P | IEA | IEA | IEA |
| response to drug | P | IEP | ||
| cholesterol absorption | P | NAS | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un | ||
| liver/biliary system phenotype | MP | Un | ||
| increased cholesterol absorption | N | ISS | ||
| arteriosclerosis | N | IAGP |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Cholestasis | D | IEP | ||
| Diabetes Mellitus, Experimental | D | IEP | ||
| Arteriosclerosis | D | IAGPISS | ||
| Hyperlipidemia | D | IAGP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| ABC transporters - General (02010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |