IpiRecord: IPI00325943

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
basal plasma membrane	C			IDA
lateral loop	C			IDA
perinuclear region of cytoplasm	C			IDA
extracellular region	C	IDA
plasma membrane	C	NAS		ISS
cytoplasm	C	IEA	IDA	ISS
integral to membrane	C	NAS	NAS	ISS IEA
microvillus	C			IDA
membrane	C	IEA	RCA	IEA ISS
apical plasma membrane	C	IEA	IDA	ISS IDA
ubiquitin protein ligase binding	F			IPI
protein binding	F		IPI	ISS IPI
transmembrane receptor protein tyrosine kinase activity	F	IEA	RCA	IEA ISS
non-membrane spanning protein tyrosine kinase activity	F	IDA
receptor activity	F	IEA	IEA	IEA
glycoprotein binding	F			IPI
protein-tyrosine kinase activity	F	IEA	ISS	IDA
kinase activity	F		IEA
ATP binding	F	IEA	IEA IEA	IEA
receptor signaling protein tyrosine kinase activity	F	TAS		ISS
protein serine/threonine kinase activity	F			ISS
Hsp90 protein binding	F			IPI
protein kinase activity	F		IEA
epidermal growth factor receptor activity	F	NAS	RCA	ISS ISS ISS
electron carrier activity	F	IEA		IEA
nucleotide binding	F	IEA	IEA	IEA
transferase activity	F	IEA	IEA	IEA
ErbB-3 class receptor binding	F	TAS		ISS
iron-sulfur cluster binding	F	IEA		IEA
identical protein binding	F	IPI
protein heterodimerization activity	F	IDA NAS		ISS IPI
phosphoinositide-mediated signaling	P	NAS		ISS
motor axon guidance	P		IMP
regulation of progression through cell cycle	P		IEA
protein amino acid autophosphorylation	P			IDA
positive regulation of MAPK activity	P	IDA		ISS
regulation of cell differentiation	P			TAS
positive regulation of phosphoinositide 3-kinase cascade	P			IMP
glial cell differentiation	P			IGI
transmembrane receptor protein tyrosine kinase signaling pathway	P	NAS IDA	NAS	IEA ISS ISS
positive regulation of Ras protein signal transduction	P			IMP
positive regulation of MAPKKK cascade	P			IMP
negative regulation of immature T cell proliferation in the thymus	P	IEA	IMP
cell proliferation	P	TAS		ISS
central nervous system development	P			TAS
protein amino acid phosphorylation	P	TAS IEA	IEA	ISS
sympathetic nervous system development	P			IMP
positive regulation of epithelial cell proliferation	P	IDA		ISS
cellular process	P		IEA
nervous system development	P		IMP	ISS ISS
negative regulation of apoptosis	P			IMP
cell surface receptor linked signal transduction	P		ISS
heart development	P	TAS	IMP IMP	ISS ISS
neuromuscular junction development	P		IMP
response to axon injury	P			IDA
regulation of angiogenesis	P	NAS	NAS	ISS
positive regulation of cell proliferation	P			IMP
mammary gland development	P	TAS		ISS
peripheral nervous system development	P	IEA	IMP	IMP ISS
regulation of cell proliferation	P			TAS
electron transport	P	IEA		IEA
myelination	P	IEA	IMP	ISS ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (18)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
craniofacial phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un Un
behavior/neurological phenotype	MP		Un Un Un Un
lethality-embryonic/perinatal	MP		Un Un Un Un Un Un Un
skeleton phenotype	MP		Un
lethality-postnatal	MP		Un Un
muscle phenotype	MP		Un Un Un Un Un Un Un Un
life span-post-weaning/aging	MP		Un Un Un Un
growth/size phenotype	MP		Un Un Un Un
respiratory system phenotype	MP		Un Un
digestive/alimentary phenotype	MP		Un
normal phenotype	MP		Un Un
cardiovascular system phenotype	MP		Un Un Un Un Un Un
limbs/digits/tail phenotype	MP		Un Un
reproductive system phenotype	MP		Un
nervous system phenotype	MP		Un Un Un Un Un Un Un Un Un Un
increased metastatic potential	N			IED

Disease (5)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
HELLP Syndrome	D			ISS
Pre-Eclampsia	D			ISS
Myocardial Ischemia	D			ISS
Cardiomyopathy, Congestive	D			ISS
Heart Failure, Congestive	D			IEP

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
phosphatidylinositol 3 kinase-Akt signaling pathway	W			IMP
Ras mediated signalign pathway	W			IMP
mitogen activated protein kinase signaling pathway	W			IMP

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Adherens junction (04520)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Calcium signaling pathway (04020)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Dorso-ventral axis formation (04320)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Pancreatic cancer (05212)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway