IpiRecord: IPI00326685

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
external side of plasma membrane	C		IDA
plasma membrane	C			ISS
membrane	C		IEA IEA	IEA
extracellular space	C		IEA	IEA
integral to membrane	C		RCA	IEA
cytoplasmic membrane-bound vesicle	C			IDA
extracellular region	C		IEA	IEA
caveolar membrane	C			IDA
perinuclear region of cytoplasm	C			IDA
SH3 domain binding	F			ISS
tumor necrosis factor receptor binding	F		IEA	IEA
cytokine activity	F		IEA	IEA
death receptor binding	F			IC
immune response	P		IEA	IEA
apoptosis	P		IGI	IEA
positive regulation of apoptosis	P		ISS IGI
induction of apoptosis via death domain receptors	P			IMP
inflammatory cell apoptosis	P			IGI
induction of apoptosis by extracellular signals	P		IDA IDA
retinal cell programmed cell death	P		IMP
signal transduction	P		IEA	IEA
cell killing	P			ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (14)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
skin/coat/nails phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un Un
immune system phenotype	MP		Un Un
renal/urinary system phenotype	MP		Un Un
nervous system phenotype	MP		Un
respiratory system phenotype	MP		Un
liver/biliary system phenotype	MP		Un
digestive/alimentary phenotype	MP		Un
cardiovascular system phenotype	MP		Un
hematopoietic system phenotype	MP		Un Un
life span-post-weaning/aging	MP		Un Un
normal phenotype	MP		Un
neurodegeneration	N			IED

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Anemia, Aplastic	D			ISS
Carotid Stenosis	D			ISS
Arteriosclerosis	D			ISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
extrinsic death receptor pathway	W			IGI

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Apoptosis (04210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
MAPK signaling pathway (04010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Type I diabetes mellitus (04940)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cytokine-cytokine receptor interaction (04060)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway