IpiRecord: IPI00327747

IPI00327747 - Adra1b, ALPHA-1B ADRENERGIC RECEPTOR.
Uniprot Accession: P15823
Uniprot ID: ADA1B_RAT
Mapping: Chr 10, 28889639 - 28946500
Entrez Gene: 24173
Entrez MapView: Geneprod
RGD: 2054
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9288)
Rat: Adra1b, ALPHA-1B ADRENERGIC RECEPTOR.
Mouse: Adra1b, SEQUENCE.
Mouse: Adra1b, ADRENERGIC RECEPTOR, ALPHA 1B.
Rat: Adra1b, ADRENERGIC RECEPTOR, ALPHA 1B.
Human: ADRA1B, ALPHA-1B ADRENERGIC RECEPTOR.

Annotations for Adra1b and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCISS 
integral to membrane of membrane fractionCIEA IDA ISS 
integral to membraneCIEA IEA IEA 
membraneCIEA IEA IEA 
membrane fractionCIDA 
integral to plasma membraneCTAS ISS 
adrenoceptor activityFIEA RCA IEA ISS 
rhodopsin-like receptor activityFIEA IEA IEA 
receptor activityFIEA IEA IEA 
protein heterodimerization activityFISS 
G-protein coupled receptor activityFIEA 
alpha1-adrenergic receptor activityFTAS IMP IMP IGI IDA IDA IEA IDA ISS ISS 
signal transducer activityFIEA 
positive regulation of heart contraction rate by epinephrine-norepinephrinePIEA IGI ISS 
response to steroid hormone stimulusPIMP 
G-protein signaling, coupled to cAMP nucleotide second messengerPTAS ISS 
adult heart developmentPIEA IGI ISS 
G-protein coupled receptor protein signaling pathwayPTAS IEA IEA IEA ISS 
phospholipase C activationPISS 
cell proliferationPTAS ISS 
cell-cell signalingPTAS ISS 
protein kinase cascadePTAS ISS 
vasoconstriction of artery during baroreceptor response to lowering of blood pressurePIEA IMP ISS 
response to morphinePIEA IMP ISS 
blood pressure regulationPISS 
behavioral response to cocainePIEA IMP ISS 
visual learningPIEA IMP ISS 
signal transductionPIEA IEA IEA 
organ growthPIEA IGI ISS 
response to estrogen stimulusPIEP 
negative regulation of glycogen catabolic processPIEA IMP ISS 
glucose homeostasisPIEA IMP ISS 
cell growthPIEA IGI ISS 
locomotory behaviorPIEA IMP ISS 
elevation of cytosolic calcium ion concentrationPIDA 
positive regulation of glycogen catabolic processPIEA IMP ISS 
response to amphetaminePIEA IMP IMP ISS 
blood vessel remodelingPIEA IMP ISS 
response to drugPIEP 
response to hormone stimulusPIMP 
multicellular organismal developmentPTAS ISS 
increased strength of heart contraction by epinephrine-norepinephrinePIEA IGI ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (10)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
adipose tissue phenotypeMPUn
behavior/neurological phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
muscle phenotypeMPUn
renal/urinary system phenotypeMPUn
nervous system phenotypeMPUn
cardiovascular system phenotypeMPUn
digestive/alimentary phenotypeMPUn
life span-post-weaning/agingMPUn

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Insulin ResistanceDISS
HyperinsulinemiaDISS
HypertensionDISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
G protein signaling pathway via Galphaq familyWISS

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Neuroactive ligand-receptor interaction (04080)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Calcium signaling pathway (04020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway