IpiRecord: IPI00327967

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
integral to plasma membrane	C	TAS
Golgi apparatus	C			IDA
dendrite	C			IDA
endomembrane system	C			IDA
integral to membrane	C	IEA	IEA IEA	TAS IMP IEA
membrane	C		IEA
cytoplasm	C		IDA	ISS IEA
organelle outer membrane	C			IDA
cytoplasmic vesicle	C			IDA
endosome	C		IDA	ISS IEA
plasma membrane	C	TAS	IDA IDA	ISS IDA
protein self-association	F			IMP
G-protein alpha-subunit binding	F			IMP
angiotensin type I receptor activity	F		IDA	IDA ISS IMP IEA
angiotensin type II receptor activity	F	NAS IEA	IEA	IEA
protein binding	F		IPI	IPI IPI
signal transducer activity	F		IEA
G-protein coupled receptor activity	F		IEA
peptide hormone binding	F			IMP IMP
receptor activity	F	IEA	IEA	IEA
C-X-C chemokine receptor activity	F	IEA
rhodopsin-like receptor activity	F	IEA	IEA	IEA
bradykinin receptor activity	F	IEA	IEA	IEA
renin secretion into blood stream	P		IMP	ISS IEA
regulation of blood pressure by circulatory renin-angiotensin	P		IGI	ISS IEA
positive regulation of receptor recycling	P			IDA
fluid secretion	P	NR
renin-angiotensin regulation of aldosterone production	P		IMP	ISS IEA
brain renin-angiotensin system	P		IMP	ISS IEA
regulation of pH	P			IDA
signal transduction	P	IEA	IEA	IEA
drinking behavior	P		IGI IMP IMP	ISS IEA
G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)	P	TAS		IDA
response to estrogen stimulus	P			IDA
angiotensin mediated regulation of renal output	P		IMP	ISS IEA
elevation of cytosolic calcium ion concentration	P	TAS
positive regulation of blood pressure	P		IDA IMP IGI
negative regulation of neuron apoptosis	P		IMP
blood pressure regulation	P			TAS
circulation	P	NAS
blood vessel development	P		IGI	ISS IEA
kidney development	P		IGI IMP	ISS IEA
G-protein coupled receptor protein signaling pathway	P	IEA	IC	ISS IMP IMP IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
behavior/neurological phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un Un
lethality-postnatal	MP		Un
life span-post-weaning/aging	MP		Un
cardiovascular system phenotype	MP		Un Un Un
renal/urinary system phenotype	MP		Un Un
increased left ventricle diastolic pressure	N			IED

Disease (8)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Hypertrophy, Left Ventricular	D			ISS
Cerebrovascular Disorders	D			ISS
Carotid Artery Diseases	D			ISS
Metabolic Syndrome X	D			ISS
Myocardial Infarction	D			ISS
Coronary Arteriosclerosis	D			ISS
Coronary Disease	D			ISS
Hypertension	D			ISSISS

Pathway (7)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
angiotensin III signaling pathway	W			TAS
Angiotensin II signaling pathway	W			TAS
G protein signaling pathway via Galphaq family	W			IMPTAS
Angiotensin III signaling pathway through the AT1 receptor	W			IMP
G protein signaling pathway via Galpha12/Galpha13 family	W			IMP
Angiotensin II signaling pathway through the AT1 receptor	W			TAS
renin-angiotensin system signaling pathway	W			TAS

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Neuroactive ligand-receptor interaction (04080)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Calcium signaling pathway (04020)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway