IpiRecord: IPI00339114

IPI00339114 - Ptpn6, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6.
Uniprot Accession: Q8R5H0
Uniprot ID: Q8R5H0_RAT
Mapping: Chr 4, 160843701 - 160856821
Entrez Gene: 116689
Entrez MapView: Geneprod
RGD: 620660
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4987)
Rat: Ptpn6, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6.
Mouse: Ptpn6, ISOFORM 2 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6.
Mouse: Ptpn6, ISOFORM 3 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6.
Mouse: Ptpn6, ISOFORM 1 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6.
Human: PTPN6, ISOFORM 3 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6.
Human: PTPN6, ISOFORM 1 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6.
Human: PTPN6, ISOFORM 2 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6.
Human: PTPN6, PROTEIN.
Human: PTPN6, 19 KDA PROTEIN.
Human: PTPN6, 18 KDA PROTEIN.
Human: PTPN6, 70 KDA SHP-1L PROTEIN.

Annotations for Ptpn6 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cellular_componentCND 
membraneCISS 
cytoplasmCTAS ISS 
cytoskeletonCISS 
hydrolase activityFIEA RCA ISS IEA 
phosphoric monoester hydrolase activityFIEA IEA 
prenylated protein tyrosine phosphatase activityFRCA ISS 
protein bindingFIPI IPI ISS ISS IEA 
phosphotyrosine bindingFIPI ISS IEA 
molecular_functionFND 
phosphoprotein phosphatase activityFRCA ISS 
protein tyrosine phosphatase activityFIEA IDA TAS ISS ISS IEA 
cytokine and chemokine mediated signaling pathwayPTAS ISS 
protein amino acid dephosphorylationPIEA RCA TAS ISS ISS IEA 
negative regulation of cell proliferationPNAS 
apoptosisPISS 
intracellular signaling cascadePIEA IDA ISS IEA 
response to woundingPIEP 
dephosphorylationPIEA 
G-protein coupled receptor protein signaling pathwayPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
immune system phenotypeMPUn
respiratory system phenotypeMPUn
hematopoietic system phenotypeMPUn
life span-post-weaning/agingMPUn
pigmentation phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Jak-STAT signaling pathway (04630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway