| IPI00339114 - Ptpn6, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6. | |
|---|---|
| Uniprot Accession: Q8R5H0 | |
| Uniprot ID: Q8R5H0_RAT | |
| Mapping: Chr 4, 160843701 - 160856821 | |
| Entrez Gene: 116689 | |
| Entrez MapView: |
|
| RGD: 620660 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4987) |
|---|
| Rat: Ptpn6, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6. |
| Mouse: Ptpn6, ISOFORM 2 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6. |
| Mouse: Ptpn6, ISOFORM 3 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6. |
| Mouse: Ptpn6, ISOFORM 1 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6. |
| Human: PTPN6, ISOFORM 3 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6. |
| Human: PTPN6, ISOFORM 1 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6. |
| Human: PTPN6, ISOFORM 2 OF TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6. |
| Human: PTPN6, PROTEIN. |
| Human: PTPN6, 19 KDA PROTEIN. |
| Human: PTPN6, 18 KDA PROTEIN. |
| Human: PTPN6, 70 KDA SHP-1L PROTEIN. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular_component | C | ND | ||
| membrane | C | ISS | ||
| cytoplasm | C | TAS | ISS | |
| cytoskeleton | C | ISS | ||
| hydrolase activity | F | IEA | RCA | ISS IEA |
| phosphoric monoester hydrolase activity | F | IEA | IEA | |
| prenylated protein tyrosine phosphatase activity | F | RCA | ISS | |
| protein binding | F | IPI IPI | ISS ISS IEA | |
| phosphotyrosine binding | F | IPI | ISS IEA | |
| molecular_function | F | ND | ||
| phosphoprotein phosphatase activity | F | RCA | ISS | |
| protein tyrosine phosphatase activity | F | IEA | IDA | TAS ISS ISS IEA |
| cytokine and chemokine mediated signaling pathway | P | TAS | ISS | |
| protein amino acid dephosphorylation | P | IEA | RCA | TAS ISS ISS IEA |
| negative regulation of cell proliferation | P | NAS | ||
| apoptosis | P | ISS | ||
| intracellular signaling cascade | P | IEA | IDA | ISS IEA |
| response to wounding | P | IEP | ||
| dephosphorylation | P | IEA | ||
| G-protein coupled receptor protein signaling pathway | P | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| skin/coat/nails phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| respiratory system phenotype | MP | Un | ||
| hematopoietic system phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un | ||
| pigmentation phenotype | MP | Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| T cell receptor signaling pathway (04660) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| B cell receptor signaling pathway (04662) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Adherens junction (04520) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Jak-STAT signaling pathway (04630) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Natural killer cell mediated cytotoxicity (04650) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |