IpiRecord: IPI00358157

IPI00358157 - Cdk6, SIMILAR TO CYCLIN-DEPENDENT KINASE 6.
Uniprot Accession: Q99MD0
Uniprot ID: Q99MD0_RAT
Mapping: Chr 4, 27362748 - 27618018
Entrez Gene: 114483
Entrez MapView: Geneprod
RGD: 621121
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4326)
Rat: Cdk6, SIMILAR TO CYCLIN-DEPENDENT KINASE 6.
Mouse: Cdk6, CELL DIVISION PROTEIN KINASE 6.
Human: CDK6, CELL DIVISION PROTEIN KINASE 6.

Annotations for Cdk6 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nucleotide bindingFIEA IEA 
kinase activityFIEA 
protein bindingFIPI IPI IPI IPI IPI ISS ISS IDA 
protein serine/threonine kinase activityFIEA IEA IEA 
ATP bindingFIEA IEA IEA IEA 
protein kinase activityFIEA IEA 
cyclin-dependent protein kinase activityFIEA 
transferase activityFIEA IEA 
regulation of progression through cell cyclePTAS RCA ISS ISS 
cell proliferationPTAS RCA ISS ISS 
protein amino acid phosphorylationPIEA IEA IEA 
cell cyclePIEA IEA IEA 
G1 phase of mitotic cell cyclePTAS RCA ISS ISS 
cell divisionPIEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (8)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
endocrine/exocrine gland phenotypeMPUn
immune system phenotypeMPUn
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
hematopoietic system phenotypeMPUn
reproductive system phenotypeMPUn
growth/size phenotypeMPUn
liver/biliary system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cell cycle (04110)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway