IpiRecord: IPI00360064

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
postsynaptic density	C			IDA
cell soma	C			IDA
intracellular	C			IEA
plasma membrane	C			IDA
SH3 domain binding	F			IPI
protein binding	F			ISS ISS IPI
guanyl-nucleotide exchange factor activity	F			IEA
Rho GTPase activator activity	F			ISS
DNA binding	F			IEA
Ras guanyl-nucleotide exchange factor activity	F			ISS ISS
Rho guanyl-nucleotide exchange factor activity	F			ISS IEA
positive regulation of epidermal growth factor receptor signaling pathway	P			IEP
small GTPase mediated signal transduction	P			ISS
Ras protein signal transduction	P			ISS IMP
nerve growth factor receptor signaling pathway	P			IMP
regulation of Rho protein signal transduction	P			IEA
regulation of small GTPase mediated signal transduction	P			IEA
signal transduction	P			ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Fibromatosis, Gingival	D			ISS

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
nerve growth factor signaling pathway	W			IMP
epidermal growth factor/neuregulin signaling pathway	W			IEP
Ras family signaling pathway	W			IMP

KEGG Pathway (14)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Glioma (05214)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
GnRH signaling pathway (04912)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
T cell receptor signaling pathway (04660)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Chronic myeloid leukemia (05220)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Fc epsilon RI signaling pathway (04664)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
MAPK signaling pathway (04010)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Regulation of actin cytoskeleton (04810)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Gap junction (04540)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Dorso-ventral axis formation (04320)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Insulin signaling pathway (04910)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Not present in KEGG pathway	Not present in KEGG pathway	Present in KEGG pathway