IpiRecord: IPI00361821

IPI00361821 - Crkl, V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG (AVIAN)-LIKE.
Uniprot Accession: Q5U2U2
Uniprot ID: Q5U2U2_RAT
Mapping: Chr 11, 85520244 - 85554667
Entrez Gene: 287942
Entrez MapView: Geneprod
RGD: 1308531
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10649)
Rat: Crkl, V-CRK SARCOMA VIRUS CT10 ONCOGENE HOMOLOG (AVIAN)-LIKE.
Mouse: Crkl, CRK-LIKE PROTEIN.
Human: CRKL, CRK-LIKE PROTEIN.

Annotations for Crkl and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
intracellularCIEA 
protein-tyrosine kinase activityFTAS ISS 
SH3/SH2 adaptor activityFTAS ISS 
protein bindingFIPI IPI IPI ISS ISS IPI 
cell motilityPNR ISS 
cellular processPIEA 
parathyroid gland developmentPIEA IGI 
intracellular signaling cascadePTAS IEA ISS IEA 
regulation of progression through cell cyclePIEA 
heart developmentPIEA IGI 
pattern specification processPIEA IGI 
Ras protein signal transductionPTAS ISS 
protein amino acid phosphorylationPNR ISS 
thymus developmentPIEA IGI 
blood vessel developmentPIEA IGI 
anterior/posterior pattern formationPIEA IGI 
JNK cascadePTAS ISS 
organ morphogenesisPIEA IMP ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (12)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
craniofacial phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
immune system phenotypeMPUn
lethality-embryonic/perinatalMPUn
skeleton phenotypeMPUn
nervous system phenotypeMPUn
vision/eye phenotypeMPUn
cardiovascular system phenotypeMPUn
hematopoietic system phenotypeMPUn
hearing/vestibular/ear phenotypeMPUn
growth/size phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway