IpiRecord: IPI00370158

IPI00370158 - Rac2, RAS-RELATED C3 BOTULINUM SUBSTRATE 2.
Uniprot Accession: Q5U1Y2
Uniprot ID: Q5U1Y2_RAT
Mapping: Chr 7, 116520066 - 116532482
Entrez Gene: 366957
Entrez MapView: Geneprod
RGD: 1307568
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7399)
Rat: Rac2, RAS-RELATED C3 BOTULINUM SUBSTRATE 2.
Mouse: Rac2, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 PRECURSOR.
Human: RAC2, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 PRECURSOR.

Annotations for Rac2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCIEA IDA ISS 
membrane fractionCIEA IDA ISS 
intracellularCIEA IEA IEA 
nuclear envelopeCIEA IDA ISS 
membraneCIEA IEA 
GTP bindingFIEA IEA IEA IEA 
GTPase activityFTAS IDA ISS ISS 
protein bindingFIPI ISS 
nucleotide bindingFIEA IEA IEA 
cell projection biogenesisPIEA IDA ISS 
actin cytoskeleton organization and biogenesisPIEA IDA ISS IDA 
chemotaxisPIEA IDA ISS 
small GTPase mediated signal transductionPIEA IEA IEA 
positive regulation of cell proliferationPIEA IGI IMP 
signal transductionPTAS ISS 
bone resorptionPIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMPUn
hematopoietic system phenotypeMPUn

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
AbnormalitiesDISS
SyndromeDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (13)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Axon guidance (04360)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway