IpiRecord: IPI00392795

IPI00392795 - Lef1, LYMPHOID ENHANCER BINDING FACTOR 1 SHORT ISOFORM.
Uniprot Accession: A5A1E7
Uniprot ID: A5A1E7_RAT
Mapping: Chr 2, 228550263 - 228689323
Entrez Gene: 161452
Entrez MapView: Geneprod
RGD: 620241
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2620)
Rat: Lef1, LYMPHOID ENHANCER-BINDING FACTOR 1.
Mouse: Lef1, ISOFORM 1 OF LYMPHOID ENHANCER-BINDING FACTOR 1.
Mouse: Lef1, FULL INSERT SEQUENCE.
Mouse: Lef1, INSERT SEQUENCE.
Mouse: Lef1, INSERT SEQUENCE.
Mouse: Lef1, 41 KDA PROTEIN.
Rat: Lef1, LYMPHOID ENHANCER BINDING FACTOR 1 SHORT ISOFORM.
Human: LEF1, ISOFORM 1 OF LYMPHOID ENHANCER-BINDING FACTOR 1.
Human: LEF1, ISOFORM 2 OF LYMPHOID ENHANCER-BINDING FACTOR 1.
Human: LEF1, ISOFORM 3 OF LYMPHOID ENHANCER-BINDING FACTOR 1.
Human: LEF1, ISOFORM 4 OF LYMPHOID ENHANCER-BINDING FACTOR 1.
Human: LEF1, LEF1 PROTEIN.

Annotations for Lef1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCIDA ISS 
transcription factor complexCIPI ISS 
nucleusCIDA IDA ISS IEA 
transcription factor activityFIDA IDA IDA ISS 
transcription activator activityFIDA 
RNA polymerase II transcription factor activity, enhancer bindingFIGI ISS 
DNA bindingFIEA IDA IDA ISS 
DNA bending activityFIDA ISS 
protein bindingFIPI ISS ISS IPI 
chromatin bindingFIDA IDA IDA ISS 
embryonic limb morphogenesisPIGI 
dentate gyrus developmentPIMP 
mammary gland developmentPIMP 
positive regulation of transcription, DNA-dependentPIDA 
Wnt receptor signaling pathwayPIMP IEA 
cell developmentPIGI ISS 
transcriptionPIEA IEA 
hippocampus developmentPIMP 
regulation of transcription, DNA-dependentPIEA IEA IEA IEA 
negative regulation of striated muscle developmentPIDA 
placenta developmentPIGI 
regulation of transcription from RNA polymerase II promoterPIDA ISS 
positive regulation of transcription from RNA polymerase II promoterPIDA IDA ISS 
paraxial mesoderm formationPIGI 
negative regulation of transcription from RNA polymerase II promoterPIDA 
odontogenesis (sensu Vertebrata)PIMP ISS 
regulation of Wnt receptor signaling pathwayPIGI 
somitogenesisPIMP IGI ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
craniofacial phenotypeMPUn
adipose tissue phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
skeleton phenotypeMPUn
nervous system phenotypeMPUn Un
touch/vibrissae phenotypeMPUn
reproductive system phenotypeMPUn
pigmentation phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway