| IPI00454514 - Il4, INTERLEUKIN 4. | |
|---|---|
| Uniprot Accession: Q6RIC4 | |
| Uniprot ID: Q6RIC4_RAT | |
| Mapping: Chr 10, 39074582 - 39080134 | |
| Entrez Gene: 287287 | |
| Entrez MapView: |
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| RGD: 2898 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9364) |
|---|
| Rat: Il4, INTERLEUKIN-4 PRECURSOR. |
| Mouse: Il4, INTERLEUKIN-4 PRECURSOR. |
| Rat: Il4, INTERLEUKIN 4. |
| Human: IL4, ISOFORM 1 OF INTERLEUKIN-4 PRECURSOR. |
| Human: IL4, ISOFORM 2 OF INTERLEUKIN-4 PRECURSOR. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| extracellular region | C | IEA | TAS IEA | |
| extracellular space | C | IDA IDA IDA | ISS ISS IEA | |
| growth factor activity | F | IEA IEA | ||
| cytokine activity | F | IDA IDA IDA IDA | TAS ISS | |
| protein binding | F | IPI | ISS IEA | |
| hematopoietin/interferon-class (D200-domain) cytokine receptor binding | F | IEA | ||
| interleukin-4 receptor binding | F | IEA | ISS IEA | |
| regulation of phosphorylation | P | IDA | ISS IEA | |
| B cell activation | P | IEA | IEA | |
| negative regulation of apoptosis | P | IDA | ISS IEA | |
| positive regulation of isotype switching to IgE isotypes | P | IDA | ISS IEA | |
| B cell differentiation | P | ISS | ||
| cellular defense response | P | ISS | ||
| positive regulation of peptidyl-tyrosine phosphorylation | P | IDA | ||
| connective tissue growth factor biosynthetic process | P | ISS | ||
| inflammatory response | P | NAS | ||
| positive regulation of B cell proliferation | P | IDA | ISS IEA | |
| cholesterol metabolic process | P | IMP | IEA | |
| negative regulation of osteoclast differentiation | P | IDA | ISS IEA | |
| immune response | P | IEA | IEA | |
| positive regulation of isotype switching to IgG isotypes | P | IDA IDA | ISS IEA | |
| positive regulation of MHC class II biosynthetic process | P | IDA | ISS IEA | |
| positive regulation of tyrosine phosphorylation of Stat5 protein | P | IDA | ISS IEA | |
| positive regulation of activated T cell proliferation | P | IDA | ISS IEA | |
| regulation of isotype switching | P | ISS | ||
| chemotaxis | P | ISS | ||
| positive regulation of T cell proliferation | P | IDA | ISS | |
| T-helper 2 type immune response | P | ISS | ||
| positive regulation of transcription from RNA polymerase II promoter | P | IDA IGI | ISS IEA | |
| regulation of immune response | P | IDA | ISS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un | ||
| immune system phenotype | MP | Un Un Un Un Un | ||
| lethality-postnatal | MP | Un | ||
| vision/eye phenotype | MP | Un | ||
| normal phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un Un | ||
| hematopoietic system phenotype | MP | Un Un | ||
| liver/biliary system phenotype | MP | Un | ||
| no phenotypic analysis | MP | Un Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| T cell receptor signaling pathway (04660) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Fc epsilon RI signaling pathway (04664) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Jak-STAT signaling pathway (04630) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Hematopoietic cell lineage (04640) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cytokine-cytokine receptor interaction (04060) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |