IpiRecord: IPI00471549

IPI00471549 - Il2rg, INTERLEUKIN 2 RECEPTOR, GAMMA.
Uniprot Accession: Q8VHR8
Uniprot ID: Q8VHR8_RAT
Mapping: Chr X, 89339271 - 89346542
Entrez Gene: 140924
Entrez MapView: Geneprod
RGD: 621466
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14867)
Rat: Il2rg, INTERLEUKIN 2 RECEPTOR, GAMMA.
Mouse: Il2rg, CYTOKINE RECEPTOR COMMON GAMMA CHAIN PRECURSOR.
Rat: Il2rg, AB2-183.
Rat: Il2rg, 22 KDA PROTEIN.
Human: IL2RG, CYTOKINE RECEPTOR COMMON GAMMA CHAIN PRECURSOR.
Human: IL2RG, IL2RG NIRS VARIANT 4.
Human: IL2RG, IL2RG NIRS VARIANT 1.
Human: IL2RG, IL2RG NIRS VARIANT 3.

Annotations for Il2rg and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to membraneCRCA ISS NAS 
integral to plasma membraneCTAS ISS 
membraneCIEA IEA IEA IEA 
external side of plasma membraneCISS IDA ISS 
cell surfaceCIMP 
hematopoietin/interferon-class (D200-domain) cytokine receptor activityFIEA IEA 
cytokine bindingFTAS 
interleukin-2 receptor activityFTAS ISS 
protein bindingFIPI IPI ISS 
interleukin-7 bindingFIMP 
interleukin receptor activityFTAS 
receptor activityFIEA IEA IEA 
interleukin-2 bindingFIPI ISS IMP 
interleukin-4 receptor activityFTAS ISS 
interleukin-7 receptor activityFTAS ISS 
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiationPIMP 
immune responsePTAS ISS TAS 
signal transductionPNAS ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (3)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMP####
digestive/alimentary phenotypeMP#
hematopoietic system phenotypeMP###

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Severe Combined ImmunodeficiencyDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Jak-STAT signaling pathway (04630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway