| IPI00554141 - Cxcr4, C-X-C CHEMOKINE RECEPTOR TYPE 4. | |
|---|---|
| Uniprot Accession: Q62973 | |
| Uniprot ID: Q62973_RAT | |
| Mapping: Chr 13, 41308286 - 41312170 | |
| Entrez Gene: 60628 | |
| Entrez MapView: |
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| RGD: 620465 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11222) |
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| Rat: Cxcr4, C-X-C CHEMOKINE RECEPTOR TYPE 4. |
| Mouse: Cxcr4, ISOFORM CXCR4-B OF C-X-C CHEMOKINE RECEPTOR TYPE 4. |
| Mouse: Cxcr4, CHEMOKINE RECEPTOR 4. |
| Mouse: Cxcr4, CHEMOKINE (C-X-C MOTIF) RECEPTOR 4. |
| Rat: Cxcr4, CXC CHEMOKINE RECEPTOR. |
| Human: CXCR4, ISOFORM 1 OF C-X-C CHEMOKINE RECEPTOR TYPE 4. |
| Human: CXCR4, ISOFORM 2 OF C-X-C CHEMOKINE RECEPTOR TYPE 4. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| growth cone | C | IDA | ISS | |
| integral to membrane | C | RCA | IEA ISS TAS | |
| membrane | C | IEA | IEA | |
| endosome | C | IDA | ||
| purinergic nucleotide receptor activity, G-protein coupled | F | RCA | ISS | |
| rhodopsin-like receptor activity | F | IEA | IEA | |
| receptor activity | F | IEA | IEA | |
| G-protein coupled receptor activity | F | IEA | ||
| C-C chemokine receptor activity | F | IEA | IEA TAS | |
| chemokine receptor activity | F | IEA | ||
| C-X-C chemokine receptor activity | F | RCA | IEA TAS ISS | |
| signal transducer activity | F | IEA | ||
| motor axon guidance | P | IMP | ISS | |
| T cell proliferation | P | IMP | ISS | |
| ameboidal cell migration | P | IMP | ISS | |
| defense response | P | IEA | ||
| cardiac muscle contraction | P | IMP | ||
| neuron recognition | P | IEP | ||
| neuron migration | P | IDA | IDA ISS IMP | |
| regulation of cell migration | P | IMP IMP IGI | ISS | |
| G-protein coupled receptor protein signaling pathway | P | IEA IEA | IEA | |
| regulation of calcium ion transport | P | IMP | ||
| epithelial cell development | P | IMP | ||
| chemotaxis | P | IEA | ||
| nervous system development | P | TAS | ||
| germ cell migration | P | IMP | ISS | |
| germ cell development | P | IMP | ISS | |
| signal transduction | P | IEA | IEA | |
| organ morphogenesis | P | TAS | ||
| regulation of programmed cell death | P | IMP | ||
| cell migration | P | IMP | ||
| regulation of chemotaxis | P | IMP | ||
| brain development | P | IMP | ISS ISS | |
| patterning of blood vessels | P | IMP | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| homeostasis/metabolism phenotype | MP | Un | ||
| embryogenesis phenotype | MP | Un | ||
| immune system phenotype | MP | Un Un Un Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un Un | ||
| muscle phenotype | MP | Un | ||
| renal/urinary system phenotype | MP | Un | ||
| nervous system phenotype | MP | Un Un | ||
| respiratory system phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un Un Un | ||
| digestive/alimentary phenotype | MP | Un Un | ||
| reproductive system phenotype | MP | Un Un | ||
| hematopoietic system phenotype | MP | Un Un Un Un Un | ||
| growth/size phenotype | MP | Un Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Warts | D | ISS | ||
| Neutropenia | D | ISS | ||
| Agammaglobulinemia | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Leukocyte transendothelial migration (04670) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Axon guidance (04360) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Cytokine-cytokine receptor interaction (04060) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |