IpiRecord: IPI00554334

IPI00554334 - Pik3r2, PHOSPHATIDYLINOSITOL 3-KINASE, REGULATORY SUBUNIT, POLYPEPTIDE 2.
Uniprot Accession: Q5FVS6
Uniprot ID: Q5FVS6_RAT
Mapping: Chr 16, 19171101 - 19179650
Entrez Gene: 29741
Entrez MapView: Geneprod
RGD: 68341
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12749)
Rat: Pik3r2, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA.
Mouse: Pik3r2, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA.
Rat: Pik3r2, PHOSPHATIDYLINOSITOL 3-KINASE, REGULATORY SUBUNIT, POLYPEPTIDE 2.
Human: PIK3R2, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA.
Human: PIK3R2, PIK3R2 PROTEIN.

Annotations for Pik3r2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
intracellularCIEA IEA IEA 
phosphoinositide 3-kinase complexCIEA NAS IEA 
phosphoinositide 3-kinase regulator activityFIEA IEA IEA 
protein bindingFIPI IPI ISS ISS IEA 
kinase activityFIEA IEA 
1-phosphatidylinositol-3-kinase activityFISS IMP ISS 
insulin receptor signaling pathwayPNAS 
regulation of phosphorylationPNAS 
intracellular signaling cascadePIEA IEA IEA 
signal transductionPIEA 
negative regulation of anti-apoptosisPISS IMP ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (3)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
muscle phenotypeMPUn
cardiovascular system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
mTOR signaling pathway (04150)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Jak-STAT signaling pathway (04630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Type II diabetes mellitus (04930)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Phosphatidylinositol signaling system (04070)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway