IpiRecord: IPI00555215
| IPI00555215 - Prkaca, ISOFORM 2 OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT. | |
|---|---|
| Uniprot Accession: P27791-2 | |
| Uniprot ID: KAPCA_RAT | |
| Mapping: Chr 19, 25837118 - 25864844 | |
| Entrez Gene: 25636 | |
| Entrez MapView: |
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| RGD: 3389 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13951) |
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| Rat: Prkaca, ISOFORM 1 OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT. |
| Mouse: Prkaca, ISOFORM 2 OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT. |
| Mouse: Prkaca, ISOFORM 1 OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT. |
| Mouse: Prkaca, 30 KDA PROTEIN. |
| Rat: Prkaca, ISOFORM 2 OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT. |
| Rat: Prkaca, 46 KDA PROTEIN. |
| Rat: Prkaca, PROTEIN KINASE, CAMP-DEPENDENT, CATALYTIC, ALPHA. |
| Human: PRKACA, ISOFORM 2 OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT. |
| Human: PRKACA, ISOFORM 1 OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT. |
Annotations for Prkaca and orthologs
GO Annotation Table
Compiled GO Annotations (from IPI)
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| nucleus | C | IEA | IDA | |
| cytoplasm | C | IDA | ISS IDA | |
| plasma membrane | C | IDA | ||
| mitochondrion | C | IDA | ISS | |
| cAMP-dependent protein kinase complex | C | ISS | ||
| membrane fraction | C | IDA | ||
| Golgi apparatus | C | IDA | ||
| neuromuscular junction | C | IDA | ||
| protein-tyrosine kinase activity | F | ISS | ||
| protein serine/threonine kinase activity | F | IEA IEA | IEA | |
| transferase activity | F | IEA | ||
| cAMP-dependent protein kinase activity | F | IDA | ISS ISS ISS IDA | |
| protein kinase activity | F | IDA | ISS | |
| ATP binding | F | IEA IEA | ISS IEA | |
| protein binding | F | IPI | ISS ISS | |
| kinase activity | F | IEA | ||
| nucleotide binding | F | IEA | ||
| protein amino acid phosphorylation | P | IDA | ISS ISS IEA | |
| peptidyl-serine phosphorylation | P | IDA | ||
| regulation of synaptic transmission, glutamatergic | P | IDA | ||
| mesoderm formation | P | IGI | ISS | |
| regulation of cellular respiration | P | IDA |
Cellular Component
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Biological Process
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Molecular Function
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Phenotype (12)
Compiled Mammalian Phenotype Ontology Annotations (from IPI)
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| adipose tissue phenotype | MP | Un | ||
| endocrine/exocrine gland phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| skeleton phenotype | MP | Un | ||
| lethality-postnatal | MP | Un | ||
| renal/urinary system phenotype | MP | Un | ||
| nervous system phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un | ||
| reproductive system phenotype | MP | Un Un | ||
| growth/size phenotype | MP | Un Un |
Disease (2)
Compiled Disease Ontology Annotations (from IPI)
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Cardiomyopathy, Hypertrophic | D | ISS | ||
| Heart Failure, Congestive | D | ISS |
Pathway (4)
Compiled Pathway Ontology Annotations (from IPI)
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Wnt signaling pathway | W | IEA | ||
| Parkinson disease pathway | W | IEA | ||
| programmed cell death pathway | W | IEA | ||
| mitogen activated protein kinase signaling pathway | W | IEA |
KEGG Pathway (0)
KEGG Pathways for this protein (from IPI)
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| GnRH signaling pathway (04912) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Hedgehog signaling pathway (04340) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Olfactory transduction (04740) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Apoptosis (04210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Taste transduction (04742) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Wnt signaling pathway (04310) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Calcium signaling pathway (04020) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Gap junction (04540) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Insulin signaling pathway (04910) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Long-term potentiation (04720) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
© MCW Proteomics Center, 2006-2008
Supported by funds from the National Heart, Lung and Blood Institute