IpiRecord: IPI00561647

IPI00561647 - Hsd17b4, PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2.
Uniprot Accession: P70540
Uniprot ID: P70540_RAT
Mapping: Chr 18, 45157435 - 45251530
Entrez Gene: 79244
Entrez MapView: Geneprod
RGD: 621806
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13615)
Rat: Hsd17b4, HSD17B4 PROTEIN.
Mouse: Hsd17b4, PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2.
Rat: Hsd17b4, PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2.
Human: HSD17B4, PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2.
Human: HSD17B4, SIMILAR TO PEROXISOMAL MULTIFUNCTIONAL PROTEIN 2.

Annotations for Hsd17b4 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
peroxisomeCTAS TAS IDA ISS IDA IDA 
mitochondrionCIEA IDA ISS 
protein bindingFIPI 
lyase activityFIEA IEA IEA 
3(or 17)beta-hydroxysteroid dehydrogenase activityFTAS 
3-hydroxyacyl-CoA dehydrogenase activityFIEA IEA IEA 
sterol carrier activityFTAS IEA IEA ISS IEA 
isomerase activityFIEA IEA IEA 
oxidoreductase activityFIEA IEA IEA IEA 
sterol transporter activityFTAS ISS 
estradiol 17-beta-dehydrogenase activityFTAS ISS 
lipid metabolic processPIEA IEA IEA 
fatty acid metabolic processPIEA IEA IEA 
metabolic processPIEA IEA IEA 
Sertoli cell developmentPIMP 
very-long-chain fatty acid metabolic processPIMP 
protein targetingPRCA ISS 
fatty acid beta-oxidationPIMP 
cholesterol metabolic processPNAS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (12)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn
behavior/neurological phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
lethality-embryonic/perinatalMPUn
lethality-postnatalMPUn
muscle phenotypeMPUn
nervous system phenotypeMPUn
vision/eye phenotypeMPUn
digestive/alimentary phenotypeMPUn
reproductive system phenotypeMPUn
growth/size phenotypeMPUn
liver/biliary system phenotypeMPUn

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Lipid Metabolism, Inborn ErrorsDISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
androgen and estrogen metabolic pathwayWIEA

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Caprolactam degradation (00930)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fatty acid metabolism (00071)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Lysine degradation (00310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tryptophan metabolism (00380)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Valine, leucine and isoleucine degradation (00280)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Butanoate metabolism (00650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fatty acid elongation in mitochondria (00062)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway