| IPI00565862 - Rock2, RHO-ASSOCIATED PROTEIN KINASE 2. | |
|---|---|
| Uniprot Accession: Q62868 | |
| Uniprot ID: ROCK2_RAT | |
| Mapping: Chr 6, 40581295 - 40667231 | |
| Entrez Gene: 25537 | |
| Entrez MapView: |
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| RGD: 3590 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6235) |
|---|
| Rat: Rock2, RHO-ASSOCIATED PROTEIN KINASE 2. |
| Mouse: Rock2, RHO-ASSOCIATED PROTEIN KINASE 2. |
| Human: ROCK2, RHO-ASSOCIATED PROTEIN KINASE 2. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| actin cytoskeleton | C | NR | ISS | |
| intracellular | C | IEA | RCA | ISS IEA |
| membrane | C | IEA | IEA | |
| cytoplasm | C | IEA | IEA | |
| zinc ion binding | F | IEA | IEA | IEA |
| nucleotide binding | F | IEA | IEA | IEA |
| diacylglycerol binding | F | IEA | IEA | IEA |
| ATP binding | F | IEA | IEA IEA | IEA |
| protein serine/threonine kinase activity | F | TAS | IEA IEA | ISS IEA |
| actin binding | F | RCA | ISS | |
| metal ion binding | F | IEA | IEA | IEA |
| protein binding | F | IPI | IPI | ISS IEA |
| structural molecule activity | F | NAS | ISS | |
| protein kinase activity | F | IEA | ||
| transferase activity | F | IEA | IEA | IEA |
| kinase activity | F | IEA | TAS | |
| protein amino acid phosphorylation | P | TAS | IEA | ISS IEA |
| actin cytoskeleton organization and biogenesis | P | IGI | ||
| muscle contraction | P | NR | ISS | |
| signal transduction | P | RCA | ISS | |
| intracellular signaling cascade | P | IEA | IEA | IEA |
| chromosome condensation | P | TAS | ||
| cytokinesis | P | NAS | IEA | ISS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| embryogenesis phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| cardiovascular system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Pathogenic Escherichia coli infection - EHEC (05130) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| TGF-beta signaling pathway (04350) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pathogenic Escherichia coli infection - EPEC (05131) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Leukocyte transendothelial migration (04670) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Wnt signaling pathway (04310) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Regulation of actin cytoskeleton (04810) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Axon guidance (04360) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |