| IPI00764183 - Mapk8, SIMILAR TO MITOGEN-ACTIVATED PROTEIN KINASE 8. | |
|---|---|
| Uniprot Accession: -NA- | |
| Uniprot ID: -NA- | |
| Mapping: Chr 16, 8925133 - 8954535 | |
| Entrez Gene: 116554 | |
| Entrez MapView: |
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| RGD: 621506 | |
| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12629) |
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| Rat: Mapk8, MITOGEN-ACTIVATED PROTEIN KINASE 8. |
| Mouse: Mapk8, MITOGEN-ACTIVATED PROTEIN KINASE 8. |
| Mouse: Mapk8, 48 KDA PROTEIN. |
| Mouse: Mapk8, JNK1 BETA1 PROTEIN KINASE. |
| Mouse: Mapk8, MAPK8 PROTEIN. |
| Mouse: Mapk8, 35 KDA PROTEIN. |
| Rat: Mapk8, SIMILAR TO MITOGEN-ACTIVATED PROTEIN KINASE 8. |
| Human: MAPK8, ISOFORM 1 OF MITOGEN-ACTIVATED PROTEIN KINASE 8. |
| Human: MAPK8, ISOFORM 2 OF MITOGEN-ACTIVATED PROTEIN KINASE 8. |
| Human: MAPK8, ISOFORM 3 OF MITOGEN-ACTIVATED PROTEIN KINASE 8. |
| Human: MAPK8, ISOFORM 4 OF MITOGEN-ACTIVATED PROTEIN KINASE 8. |
| Human: MAPK8, 16 KDA PROTEIN. |
| Human: MAPK8, UNCHARACTERIZED PROTEIN MAPK8. |
| Human: MAPK8, 11 KDA PROTEIN. |
| Human: MAPK8, MITOGEN-ACTIVATED PROTEIN KINASE 8 TRANSCRIPT VARIANT 2. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| proton-transporting two-sector ATPase complex | C | ISS | ||
| cytoplasm | C | IDA | ||
| nucleus | C | IDA | IDA | |
| vesicle | C | IDA | ||
| MAP kinase activity | F | IEA | RCA | ISS IEA |
| protein-tyrosine kinase activity | F | ISS | ||
| kinase activity | F | IDA IDA IDA | ISS | |
| protein binding | F | IPI IPI | ISS ISS IPI IEA | |
| nucleotide binding | F | IEA | IEA | IEA |
| protein kinase activity | F | IEA | IEA | |
| hydrogen ion transporting ATP synthase activity, rotational mechanism | F | ISS | ||
| transferase activity | F | IEA | IEA | IEA |
| JUN kinase activity | F | IDA | TAS ISS ISS ISS | |
| ATP binding | F | IEA | IEA IEA | IEA |
| protein serine/threonine kinase activity | F | IEA | ISS | IEA |
| hydrogen ion transporting ATPase activity, rotational mechanism | F | ISS | ||
| ATP synthesis coupled proton transport | P | ISS | ||
| response to steroid hormone stimulus | P | IEP | ||
| JUN phosphorylation | P | IMP ISS | ||
| positive regulation of dendrite morphogenesis | P | ISS | ||
| inflammatory response | P | IDA | ||
| ossification | P | IMP | ISS IEA | |
| cell motility | P | ISS | ||
| positive regulation of apoptosis | P | IEP | ||
| response to osmotic stress | P | IDA | ||
| protein amino acid phosphorylation | P | IEA | IDA | ISS IEA |
| negative regulation of apoptosis | P | ISS | IDA | |
| peptidyl-threonine phosphorylation | P | IMP | ||
| response to hydrogen peroxide | P | IDA | ||
| response to stress | P | ISS | ||
| neurite development | P | IMP | ||
| positive regulation of microtubule polymerization | P | IMP | ||
| regulation of transcription, DNA-dependent | P | IDA | ||
| JNK cascade | P | ISS ISS | ||
| signal transduction | P | IDA ISS | ||
| response to heat | P | IDA | ||
| positive regulation of cell migration | P | IDA | ||
| response to UV | P | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| adipose tissue phenotype | MP | Un | ||
| skin/coat/nails phenotype | MP | Un | ||
| cellular phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un | ||
| embryogenesis phenotype | MP | Un | ||
| immune system phenotype | MP | Un Un | ||
| lethality-embryonic/perinatal | MP | Un Un | ||
| lethality-postnatal | MP | Un Un | ||
| muscle phenotype | MP | Un | ||
| renal/urinary system phenotype | MP | Un | ||
| nervous system phenotype | MP | Un Un | ||
| respiratory system phenotype | MP | Un | ||
| vision/eye phenotype | MP | Un | ||
| tumorigenesis | MP | Un | ||
| cardiovascular system phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un | ||
| hematopoietic system phenotype | MP | Un Un | ||
| reproductive system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un | ||
| liver/biliary system phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Cardiomegaly | D | ISS | ||
| Cerebrovascular Accident | D | IED | ||
| Brain Ischemia | D | IED | ||
| Myocardial Reperfusion Injury | D | IEPIED | ||
| Reperfusion Injury | D | IED | ||
| Aortic Aneurysm, Abdominal | D | ISS | ||
| Hypertension | D | IED |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| inflammatory response pathway | W | IDA | ||
| the planar cell polarity Wnt signaling pathway | W | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| GnRH signaling pathway (04912) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Epithelial cell signaling in Helicobacter pylori infection (05120) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| Toll-like receptor signaling pathway (04620) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Adipocytokine signaling pathway (04920) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Fc epsilon RI signaling pathway (04664) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Type II diabetes mellitus (04930) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Wnt signaling pathway (04310) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Colorectal cancer (05210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pancreatic cancer (05212) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Insulin signaling pathway (04910) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |