IpiRecord: IPI00781159

IPI00781159 - Prkca, 68 KDA PROTEIN.
Uniprot Accession: -NA-
Uniprot ID: -NA-
Mapping: Chr 10, 97361597 - 97625118
Entrez Gene: 24680
Entrez MapView: Geneprod
RGD: 3395
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10119)
Rat: Prkca, PROTEIN KINASE C ALPHA TYPE.
Mouse: Prkca, PROTEIN KINASE C ALPHA TYPE.
Mouse: Prkca, CLONE:C230094C20 PRODUCT:SIMILAR TO PROTEIN KINASE C BETA 2.
Mouse: Prkca, 76 KDA PROTEIN.
Rat: Prkca, SIMILAR TO PROTEIN KINASE C ALPHA TYPE.
Rat: Prkca, 48 KDA PROTEIN.
Rat: Prkca, 68 KDA PROTEIN.
Rat: Prkca, 68 KDA PROTEIN.
Rat: Prkca, 66 KDA PROTEIN.
Human: PRKCA, PROTEIN KINASE C ALPHA TYPE.
Human: PRKCA, PRKCA PROTEIN.

Annotations for Prkca and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCIDA 
cytoplasmCIDA IDA IDA IDA ISS 
nucleusCIDA IDA ISS 
membrane fractionCTAS ISS IDA 
mitochondrionCIDA ISS 
cytosolCIDA 
synaptosomeCIDA 
ATP bindingFIEA IEA IEA IEA 
nucleotide bindingFIEA IEA IEA 
calcium-dependent protein kinase C activityFIDA IDA ISS 
diacylglycerol bindingFIEA IEA IEA 
protein serine/threonine kinase activityFIDA ISS IEA 
metal ion bindingFIEA 
calcium ion bindingFIEA IEA IEA 
protein kinase C activityFTAS IDA IDA ISS ISS IDA 
protein bindingFIPI IPI ISS ISS ISS IPI IPI 
protein kinase activityFIEA 
kinase activityFIEA 
transferase activityFIEA IEA IEA 
zinc ion bindingFIEA IEA IEA 
regulation of receptor mediated endocytosisPIMP 
regulation of peptidyl-tyrosine phosphorylationPIMP ISS 
regulation of progression through cell cyclePTAS ISS 
peptidyl-serine phosphorylationPIDA 
induction of apoptosis by intracellular signalsPIMP ISS 
neutrophil chemotaxisPIMP ISS 
negative regulation of protein kinase activityPIMP ISS 
inactivation of MAPK activityPIMP ISS 
negative regulation of protein biosynthetic processPIMP 
induction of positive chemotaxisPIMP ISS 
protein amino acid phosphorylationPIEA IDA ISS IEA 
cellular calcium ion homeostasisPIMP ISS 
intracellular signaling cascadePIEA IEA IDA IEA 
regulation of muscle contractionPIMP ISS 
positive regulation of inflammatory responsePIMP ISS 
cardiac inotropyPIMP ISS 
negative regulation of glucose importPIMP ISS 
induction of apoptosis by extracellular signalsPTAS ISS 
cell surface receptor linked signal transductionPNR ISS 
negative regulation of protein amino acid phosphorylationPIMP ISS 
peptidyl-threonine phosphorylationPIDA 
negative regulation of insulin receptor signaling pathwayPIMP ISS 
positive regulation of protein amino acid phosphorylationPIMP ISS 
establishment of protein localizationPTAS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (5)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
muscle phenotypeMPUn
tumorigenesisMPUn
cardiovascular system phenotypeMPUn
normal phenotypeMPUn

Disease (6)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Hypertrophy, Left VentricularDIED
CardiomegalyDIAGP
Pituitary NeoplasmsDISS
Hypertrophy, Right VentricularDIED
Cardiomyopathy, CongestiveDISS
HypertensionDIAGP

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
insulin signaling pathwayWISS

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
GnRH signaling pathway (04912)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term depression (04730)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cholera - Infection (05110)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Pathogenic Escherichia coli infection - EHEC (05130)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pathogenic Escherichia coli infection - EPEC (05131)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tight junction (04530)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Calcium signaling pathway (04020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term potentiation (04720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Phosphatidylinositol signaling system (04070)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway