Kegg Pathway: Apoptosis
KEGG ID: 04210
Reference Diagram
KEGG Diagram for Apoptosis
Rat
There are 75 IPI Records from this pathway found in Rattus norvegicus.
Location of Apoptosis proteins on Rat Genome
| IPI Record | Position |
|---|---|
| 1: Akt1 | 6:137640482-137657552 |
| 2: Akt2 | 1:82686233-82726544 |
| 3: Akt3 | 13:92807672-92924984 |
| 4: Apaf1 | 7:27934653-28018255 |
| 5: Bad | 1:209617373-209626292 |
| 6: Bax | 1:95932860-95938176 |
| 7: Bcl2 | 13:12730736-12905108 |
| 8: Bcl2l1 | 3:143129087-143180199 |
| 9: Bid | 4:157296383-157318481 |
| 10: Birc2 | 8:4649559-4668104 |
| 11: Birc3 | 8:4682202-4692389 |
| 12: Birc4 | X:3011520-3055048 |
| 13: Capn1 | 1:208620284-208645007 |
| 14: Capn2 | 13:98476339-98524037 |
| 15: Casp12 | 8:2083906-2110511 |
| 16: Casp3 | 16:48944226-48962420 |
| 17: Casp6 | 2:227361538-227373844 |
| 18: Casp7 | 1:262689300-262721591 |
| 19: Casp8 | 9:57389353-57437803 |
| 20: Casp9_v1 | 5:160704225-160721802 |
| 21: Cflar | 9:57309836-57361458 |
| 22: Chp | 3:106066389-106101638 |
| 23: Chuk_predicted | 1:249122847-249157179 |
| 24: Csf2rb1 | 7:116237279-116271993 |
| 25: Cycs | 18:63216914-63217231 |
| 26: Dffa | 5:166179130-166190746 |
| 27: Dffb | 5:170750825-170762034 |
| 28: Fadd | 1:205009564-205012786 |
| 29: Faslg | 13:77472950-77480210 |
| 30: Ikbkb | 16:73805082-73858088 |
| 31: Ikbkg | X:160407166-160420190 |
| 32: Il1a | 3:116913612-116923352 |
| 33: Il1b | 3:116964427-116970887 |
| 34: Il1r1 | 9:39433337-39473646 |
| 35: Il1rap | 11:76092840-76222495 |
| 36: Il3 | 10:39684691-39687041 |
| 37: IPI00369732 | 8:56895083-56994044 |
| 38: Irak1_predicted | X:159959294-159969180 |
| 39: Irak2 | 4:149543029-149616865 |
| 40: Irak3_predicted | 7:59409198-59467682 |
| 41: Irak4_predicted | 7:133054573-133081527 |
| 42: Map3k14_predicted | 10:92406829-92430131 |
| 43: Myd88 | 8:124299725-124303798 |
| 44: Nfkb1 | 2:233091020-233187501 |
| 45: Nfkb2 | 1:251521559-251527815 |
| 46: Nfkbia | 6:75729302-75732474 |
| 47: Ngfb | 2:197621794-197632945 |
| 48: Ntrk1 | 2:179838740-179855545 |
| 49: Pdcd8 | X:134868878-134908180 |
| 50: Pik3ca | 2:118640277-118670170 |
| 51: Pik3cb | 8:103886682-103957112 |
| 52: Pik3cd_predicted | 5:166735338-166750186 |
| 53: Pik3cg_predicted | 6:50444793-50477111 |
| 54: Pik3r1 | 2:32602673-32675350 |
| 55: Pik3r2 | 16:19171101-19179650 |
| 56: Pik3r3 | 5:136497494-136566473 |
| 57: Ppp3ca | 2:234333405-234408670 |
| 58: Ppp3cb | 15:4003159-4022737 |
| 59: Ppp3cc | 15:50616841-50666010 |
| 60: Ppp3r1 | 14:98047333-98131590 |
| 61: Ppp3r2 | 5:66423374-66424371 |
| 62: Prkaca | 19:25837118-25864844 |
| 63: Prkar1a | :- |
| 64: Prkar2a | 8:113746382-113805476 |
| 65: Prkar2b | 6:50234982-50325293 |
| 66: Rela | 1:208263316-208272419 |
| 67: RGD1563261_predicted | 10:55182226-55247889 |
| 68: Ripk1_predicted | 17:37185782-37211023 |
| 69: Tnf | 20:3661000-3663618 |
| 70: Tnfrsf10b_predicted | 15:50141256-50162287 |
| 71: Tnfrsf1a | 4:162172542-162185252 |
| 72: Tnfrsf6 | 1:238259337-238274745 |
| 73: Tnfsf10 | 2:113204304-113221562 |
| 74: Tp53 | 10:56399668-56411149 |
| 75: Tradd | 19:35072870-35075251 |
Mouse
There are 75 IPI Records from this pathway found in Mus musculus.
Location of Apoptosis proteins on Mouse Genome
| IPI Record | Position |
|---|---|
| 1: Aifm1 | X:44719571-44758053 |
| 2: Akt1 | :- |
| 3: Akt2 | 7:27300516-27348213 |
| 4: Akt3 | 1:178862039-178967772 |
| 5: Apaf1 | 10:90419117-90512538 |
| 6: Atm | 9:53201763-53296362 |
| 7: Bad | 19:7008905-7018937 |
| 8: Bax | 7:45329742-45334871 |
| 9: Bcl2l1 | 2:152458757-152523123 |
| 10: Bid | 6:120858471-120882453 |
| 11: Birc2 | 9:7818749-7835790 |
| 12: Birc3 | 9:7849220-7873545 |
| 13: Birc4 | X:38315952-38350134 |
| 14: Capn1 | 19:5988546-6015163 |
| 15: Capn2 | 1:184306854-184354029 |
| 16: Casp12 | 9:5345502-5373034 |
| 17: Casp3 | 8:48116235-48137523 |
| 18: Casp6 | 3:129897501-129905595 |
| 19: Casp7 | 19:56457666-56494345 |
| 20: Casp8 | 1:58739978-58791553 |
| 21: Casp9 | 4:141065688-141088051 |
| 22: Cflar | 1:58656054-58699719 |
| 23: Chuk | 19:44126647-44160756 |
| 24: Csf2rb | 15:78153275-78177290 |
| 25: Csf2rb2 | 15:78109765-78132858 |
| 26: Dffa | 4:147947946-147964450 |
| 27: Dffb | 4:152808255-152818926 |
| 28: Endog | 2:29993533-29996078 |
| 29: Fadd | 7:144387713-144391826 |
| 30: Fas | 19:34356663-34393767 |
| 31: Fasl | 1:163617366-163625172 |
| 32: Ikbkb | 8:24124758-24172108 |
| 33: Ikbkg | X:70677332-70704240 |
| 34: Il1a | 2:128991051-129001413 |
| 35: Il1b | 2:129056011-129062561 |
| 36: Il1r1 | 1:40169626-40260723 |
| 37: Il1rap | 16:26497062-26640497 |
| 38: Il3 | 11:54108726-54110700 |
| 39: Il3ra | 14:13139762-13148759 |
| 40: Irak1 | X:70266646-70276641 |
| 41: Irak2 | 6:113604278-113660787 |
| 42: Irak3 | 10:119544714-119604597 |
| 43: Irak4 | 15:94371840-94396486 |
| 44: Map3k14 | 11:103035854-103083835 |
| 45: Myd88 | 9:119184642-119188700 |
| 46: Nfkb1 | 3:135292997-135605172 |
| 47: Nfkb2 | 19:46358111-46365401 |
| 48: Nfkbia | 12:56407731-56410725 |
| 49: Ngfb | 3:102598989-102650066 |
| 50: Ntrk1 | 3:87864171-87881089 |
| 51: Pik3ca | 3:32627755-32654380 |
| 52: Pik3cb | 9:98847754-98949439 |
| 53: Pik3cd | 4:148492970-148542498 |
| 54: Pik3cg | 12:32758720-32793858 |
| 55: Pik3r1 | 13:102781018-102868441 |
| 56: Pik3r2 | 8:73697168-73705691 |
| 57: Pik3r3 | 4:115719846-115800988 |
| 58: Pik3r5 | 11:68248320-68314041 |
| 59: Ppp3ca | 3:136608220-136874773 |
| 60: Ppp3cb | 14:19288592-19335096 |
| 61: Ppp3cc | 14:68953164-69002587 |
| 62: Ppp3r1 | :- |
| 63: Ppp3r2 | 4:49699847-49703083 |
| 64: Prkaca | 8:86863093-86889980 |
| 65: Prkacb | 3:146666960-146750346 |
| 66: Prkar1a | 11:109466334-109485746 |
| 67: Prkar1b | 5:139270948-139383333 |
| 68: Prkar2a | 9:108549547-108606747 |
| 69: Prkar2b | 12:32543731-32646499 |
| 70: Rela | 19:5637490-5648130 |
| 71: Ripk1 | 13:34010339-34042635 |
| 72: Tnf | 17:34807442-34810048 |
| 73: Tnfrsf10b | 14:68502562-68518625 |
| 74: Tnfrsf1a | 6:125315374-125328103 |
| 75: Tnfsf10 | 3:27508150-27530738 |
| 76: Tradd | 8:108147415-108153738 |
| 77: Traf2 | 2:25339991-25368903 |
| 78: Trp53 | 11:69396600-69407992 |
Human
There are 75 IPI Records from this pathway found in Homo sapiens.
Location of Apoptosis proteins on Human Genome
| IPI Record | Position |
|---|---|
| 1: AIFM1 | X:129091018-129127489 |
| 2: AKT1 | 14:104306734-104333125 |
| 3: AKT2 | 19:45430084-45483036 |
| 4: AKT3 | 1:241718158-242080053 |
| 5: APAF1 | 12:97563209-97653335 |
| 6: ATM | 11:107598769-107745036 |
| 7: BAD | 11:63793878-63808740 |
| 8: BAX | 19:54149929-54156864 |
| 9: BCL2 | 18:58941559-59137593 |
| 10: BCL2L1 | 20:29715916-29774366 |
| 11: BID | 22:16596908-16637431 |
| 12: BIRC2 | 11:101723176-101754604 |
| 13: BIRC3 | 11:101693404-101713658 |
| 14: BIRC4 | X:122821558-122875510 |
| 15: CAPN1 | 11:64705792-64736048 |
| 16: CAPN2 | 1:221966657-222030343 |
| 17: CASP10 | 2:201756100-201802372 |
| 18: CASP3 | 4:185785845-185807623 |
| 19: CASP6 | 4:110829234-110844078 |
| 20: CASP7 | 10:115428953-115480652 |
| 21: CASP8 | 2:201806426-201860677 |
| 22: CASP9 | 1:15687322-15723527 |
| 23: CFLAR | 2:201689135-201737246 |
| 24: CHP | 15:39310729-39361369 |
| 25: CSF2RB | 22:35648168-35664764 |
| 26: CYCS | 7:25124802-25131480 |
| 27: DFFA | 1:10439166-10455200 |
| 28: DFFB | 1:3763705-3791853 |
| 29: ENDOG | 9:130620574-130624777 |
| 30: FADD | 11:69726917-69731134 |
| 31: FAS | 10:90739206-90765521 |
| 32: FASLG | 1:170894777-170902637 |
| 33: IKBKB | 8:42247986-42309130 |
| 34: IKBKG | X:153423653-153446455 |
| 35: IL1A | 2:113247966-113259442 |
| 36: IL1B | 2:113303808-113310827 |
| 37: IL1R1 | 2:102125678-102159788 |
| 38: IL1RAP | 3:191714585-191858537 |
| 39: IL3 | 5:131424121-131426796 |
| 40: IL3RA | X:1415509-1461581 |
| 41: IRAK1 | X:152929145-152938625 |
| 42: IRAK2 | 3:10181563-10260427 |
| 43: IRAK3 | 12:64869270-64928684 |
| 44: IRAK4 | 12:42439067-42468164 |
| 45: MAP3K14 | 17:40696278-40750148 |
| 46: MYD88 | 3:38155157-38159514 |
| 47: NFKB1 | 4:103641518-103757506 |
| 48: NFKB2 | 10:104144320-104152271 |
| 49: NFKBIA | 14:34940475-34943703 |
| 50: NGFB | 1:115630060-115682380 |
| 51: NTRK1 | 1:155052166-155118266 |
| 52: PIK3CA | 3:180349005-180435189 |
| 53: PIK3CB | 3:139856921-139960875 |
| 54: PIK3CD | 1:9634390-9711564 |
| 55: PIK3CG | 7:106292977-106334801 |
| 56: PIK3R1 | 5:67547360-67633403 |
| 57: PIK3R2 | 19:18125016-18142343 |
| 58: PIK3R3 | 1:46278399-46371054 |
| 59: PIK3R5 | 17:8722953-8756559 |
| 60: PPP3CA | 4:102163610-102487376 |
| 61: PPP3CB | 10:74866192-74925765 |
| 62: PPP3CC | 8:22354541-22454580 |
| 63: PPP3R1 | :- |
| 64: PPP3R2 | 9:103393718-103397104 |
| 65: PRKACA | 19:14063509-14089559 |
| 66: PRKACB | 1:84316329-84476769 |
| 67: PRKACG | 9:70817241-70818849 |
| 68: PRKAR1A | 17:64019705-64040503 |
| 69: PRKAR1B | 7:555905-733813 |
| 70: PRKAR2A | 3:48762099-48860274 |
| 71: PRKAR2B | 7:106472375-106589491 |
| 72: RELA | 11:65177649-65186959 |
| 73: RIPK1 | 6:3009212-3060418 |
| 74: TNF | 6:31678016-31680778 |
| 75: TNFRSF10A | 8:23104009-23138584 |
| 76: TNFRSF10B | 8:22933598-22982637 |
| 77: TNFRSF10C | 8:23016377-23030895 |
| 78: TNFRSF10D | 8:23049046-23077488 |
| 79: TNFRSF1A | 12:6308185-6321522 |
| 80: TNFSF10 | 3:173706159-173723963 |
| 81: TP53 | 17:7512464-7531642 |
| 82: TRADD | 16:65745605-65751306 |
| 83: TRAF2 | 9:138900786-138940887 |
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Recent Literature
J Exp Clin Cancer Res. 2008 Jul 18; 27(1): 20
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ABSTRACT: BACKGROUND: The objective was to understand the influence of Survivin plasmid with short hairpin RNA (shRNA) on the cell cycle, invasio